The two-0 Arizona Cardinals had been on the street Sunday to face the San Francisco 49ers. It was a low-scoring sport in Week 3 between these NFC West rivals. In the long run, the 49ers gained 16-15 on a walk-off subject purpose.
Throughout that Week 3 loss to the 49ers, Arizona Cardinals working again James Conner suffered a severe ankle damage. The 30-year-old needed to be carted off the sector. Gamers from each groups gathered round Conner to point out help for the veteran RB. Sadly, NFL insiders confirmed that James Conner suffered a season-ending ankle damage.
James Conner will miss the ultimate 14 video games of the 2025 common season for Arizona
Cardinals RB James Conner to bear ankle surgical procedure, out indefinitely. (through @RapSheet) pic.twitter.com/f9HuvF5OMi
— NFL (@NFL) September 22, 2025
After a one-yard run with 12:26 remaining within the third quarter, Cardinals working again James Conner was down because of damage. The cart needed to come out for Conner, and that’s hardly ever a superb signal. Sources confirmed after Arizona’s Week 3 loss that it was a season-ending damage for James Conner. Over his profession, Conner has missed time because of damage. Nonetheless, that is probably the most time he’ll miss in a single season.
His earlier profession low for video games performed was 10 in 2019. James Conner will solely log three video games for the 2025 season. A devastating blow to the Cardinals’ backfield. Conner stayed wholesome in 2024, beginning 16 video games and dashing for 1,000+ yards. The 30-year-old was coming off back-to-back seasons with 1,000+ dashing yards and a minimum of seven dashing touchdowns. With out Conner, the Cardinals will flip to some gamers for the rest of the yr.
James Conner with an terrible leg damage. Sucks to see, hope he comes again robust. pic.twitter.com/XrIoFkSytT
— Footballholics (@Footballholics2) September 21, 2025
Trey Benson has been Arizona’s backup working again because the 2024 season. He was a third-round choose within the 2024 draft by the Cardinals out of Florida State. Benson performed in 13 of their 17 video games final season and made a begin in Week 2. With out James Conner, Trey Benson is ready to be Arizona’s beginning RB. The 23-year-old has been ready for his alternative, and he’ll get his probability for the remainder of the 2025 season.
Together with Trey Benson, the Cardinals have Emari Demercado and Bam Knight as depth within the backfield. Demercado is in his third season. He went undrafted in 2023 out of TCU. He’s appeared in 30 video games and has made two stats for Arizona. Zonovan “Bam” Knight was the fourth-string RB on Arizona’s depth chart. Now that James Conner is out for the season, Knight might see some taking part in time to maintain the Cardinals’ backfield recent.